ABOUT APIGENIN

Chemotherapy was potentiated by E7449 and single agent experienced considerable antitumor exercise in BRCA-deficient xenografts. Furthermore, E7449 inhibited Wnt/β-catenin signaling in colon cancer mobile lines, probable through TNKS inhibition. According to this risk, E7449 stabilized axin and TNKS proteins resulting in β-catenin de-stabilizatio